Aims and Scope

NPTM welcomes high-quality original and review research covering, but not limited to:

Natural Products & Phytochemistry

• Natural-product isolation and characterization
• Phytochemistry
• Pharmacognosy
• Bioactive secondary metabolites
• Medicinal plants
• Marine natural products
• Microbial and fungal natural products
• Natural-product structural elucidation
• Bioassay-guided fractionation
• Dereplication
• Chemotaxonomy
• Biodiversity and bioprospecting

Ethnopharmacology & Traditional Medicine

• Ethnopharmacology
• Traditional medicine
• Evidence-based validation of traditional therapies
• Medicinal plant knowledge
• Phytotherapy
• Herbal medicines
• Traditional formulations
• Safety and efficacy evaluation

Descriptive ethnobotanical studies without adequate scientific or translational relevance may fall outside the journal's priority areas.

Drug Discovery & Medicinal Chemistry

• Natural-product drug discovery
• Natural-product-inspired drug design
• Medicinal chemistry
• Semi-synthetic derivatives
• Lead identification and optimization
• Structure–activity relationships
• Target-based drug discovery
• Mechanism-based therapeutics

Molecular & Experimental Pharmacology

• Molecular mechanisms of natural products
• Target identification and validation
• Enzyme inhibition
• Receptor pharmacology
• Cell signaling
• Molecular pharmacology
• Disease-relevant biological models
• Experimental therapeutics

Computational & AI-Assisted Drug Discovery

• Molecular docking
• Molecular dynamics simulations
• Virtual screening
• Pharmacophore modelling
• QSAR
• Cheminformatics
• Bioinformatics
• Network pharmacology
• Systems pharmacology
• Artificial intelligence
• Machine learning
• Multi-omics data integration

Purely computational studies should demonstrate substantial biological significance and, where appropriate, include or lead toward experimental validation.

Metabolomics & Omics Sciences

• Metabolomics
• LC-MS/MS and GC-MS profiling
• Natural-product metabolite identification
• Genomics
• Transcriptomics
• Proteomics
• Multi-omics
• Biomarker discovery
• Systems biology

Pharmacokinetics, Safety & Toxicology

• ADME
• Pharmacokinetics
• Pharmacodynamics
• Bioavailability
• Drug metabolism
• Toxicology
• Safety pharmacology
• Herb–drug interactions
• Dose-response relationships

Preclinical & Translational Research

• In vitro therapeutic validation
• In vivo disease models
• Preclinical efficacy
• Mechanistic validation
• Translational biomarkers
• Target validation
• Experimental therapeutics
• Proof-of-concept studies

Clinical & Translational Medicine

• Clinical evaluation of natural products
• Phytopharmaceuticals
• Natural-product-based therapeutic interventions
• Translational pharmacology
• Clinical pharmacology
• Evidence-based complementary medicine
• Biomarker-guided translation

Nutraceuticals & Functional Products

• Nutraceuticals
• Functional foods
• Bioactive food components
• Dietary natural products
• Health-promoting natural compounds

Studies should demonstrate clear mechanistic, pharmacological, clinical, or translational relevance rather than routine food-composition analysis alone.

By achieving these scope, Natural Products and Translational Medicine aims to be a vital resource for the dental community, driving forward the science and practice of dentistry for the benefit of all.